Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease

Vascular dysfunction and structural abnormalities in Alzheimer’s disease (AD) are known to contribute to the progression of the pathology, and studies have tended to ignore the role of the vasculature in AD progression. We utilized the 3xTg-AD mouse model of AD to examine individual cerebral vessels...

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Bibliographic Details
Main Authors: Amandine Jullienne, Ryan Quan, Jenny I. Szu, Michelle V. Trinh, Erik J. Behringer, Andre Obenaus
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/10/8/1967