A High-Throughput Screening Identifies MICU1 Targeting Compounds
Summary: Mitochondrial Ca2+ uptake depends on the mitochondrial calcium uniporter (MCU) complex, a highly selective channel of the inner mitochondrial membrane (IMM). Here, we screen a library of 44,000 non-proprietary compounds for their ability to modulate mitochondrial Ca2+ uptake. Two of them, n...
| 主要な著者: | , , , , , , , , , , , , , , , |
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| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Elsevier
2020-02-01
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| シリーズ: | Cell Reports |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S2211124720301157 |