Allelic Expression Imbalance Analysis Identified <i>YAP1</i> Amplification in p53- Dependent Osteosarcoma

Osteosarcoma (OS) is a primary bone malignancy that mainly occurs during adolescent growth, suggesting that bone growth plays an important role in the aetiology of the disease. Genetic factors, such as heritable mutations of <i>Rb1</i> and <i>TP53,</i> are associated with an...

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Bibliographic Details
Main Authors: Guanglin Niu, Agnieszka Bak, Melanie Nusselt, Yue Zhang, Hubert Pausch, Tatiana Flisikowska, Angelika E. Schnieke, Krzysztof Flisikowski
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/6/1364