The infection of microvascular endothelial cells with ExoU-producing Pseudomonas aeruginosa triggers the release of von Willebrand factor and platelet adhesion

The infection of microvascular endothelial cells with ExoU-producing Pseudomonas aeruginosa triggers the release of von Willebrand factor and platelet adhesion

An increased plasma concentration of von Willebrand factor (vWF) is detected in individuals with many infectious diseases and is accepted as a marker of endothelium activation and prothrombotic condition. To determine whether ExoU, a Pseudomonas aeruginosa cytotoxin with proinflammatory activity, en...

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Bibliographic Details
Main Authors: Carla Freitas, Maria-Cristina Assis, Alessandra Mattos Saliba, Veronica Maria Morandi, Camila Castro Figueiredo, Mirian Pereira, Maria-Cristina Plotkowski
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2012-09-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Pseudomonas aeruginosa
von Willebrand factor
prothrombotic activity
microparticles
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000600004&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762012000600004&lng=en&tlng=en

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