Epigenetic regulation in opioid induced hyperalgesia
About 25 million American adults experience pain daily and one of the most commonly prescribed drugs to treat pain are opioids. Prolonged opioid usage and dose escalations can cause a paradoxical response where patients experience enhanced pain sensitivity. This opioid induced hyperalgesia (OIH) is...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-08-01
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Series: | Neurobiology of Pain |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2452073X23000338 |