Epigenetic regulation in opioid induced hyperalgesia

Epigenetic regulation in opioid induced hyperalgesia

About 25 million American adults experience pain daily and one of the most commonly prescribed drugs to treat pain are opioids. Prolonged opioid usage and dose escalations can cause a paradoxical response where patients experience enhanced pain sensitivity. This opioid induced hyperalgesia (OIH) is...

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Bibliographic Details
Main Authors:	Deepa Reddy, Jason R. Wickman, Seena K. Ajit
Format:	Article
Language:	English
Published:	Elsevier 2023-08-01
Series:	Neurobiology of Pain
Subjects:	Opioid induced hyperalgesia Pain Mu opioid receptor Epigenetics microRNAs
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452073X23000338

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