Ultrapotent class I neutralizing antibodies post Omicron breakthrough infection overcome broad SARS-CoV-2 escape variantsResearch in context

Ultrapotent class I neutralizing antibodies post Omicron breakthrough infection overcome broad SARS-CoV-2 escape variantsResearch in context

Summary: Background: The spread of emerging SARS-CoV-2 immune escape sublineages, especially JN.1 and KP.2, has resulted in new waves of COVID-19 globally. The evolving memory B cell responses elicited by the parental Omicron variants to subvariants with substantial antigenic drift remain incomplet...

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Bibliographic Details
Main Authors: Mengxiao Luo, Runhong Zhou, Bingjie Tang, Hang Liu, Bohao Chen, Na Liu, Yufei Mo, Pengfei Zhang, Ye Lim Lee, Jonathan Daniel Ip, Allen Wing-Ho Chu, Wan-Mui Chan, Hiu-On Man, Yuting Chen, Kelvin Kai-Wang To, Kwok-Yung Yuen, Shangyu Dang, Zhiwei Chen
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:EBioMedicine
Subjects:
SARS-CoV-2
Omicron breakthrough infection
Broadly neutralizing antibody
Structural fitness of antibody
Prevention of XBB.1.5 transmission
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424003906

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http://www.sciencedirect.com/science/article/pii/S2352396424003906

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