Impact of corticosteroids on the duration of ventilatory support during severe acute exacerbations of chronic obstructive pulmonary disease in patients in the intensive care unit: a study protocol for a multicentre, randomized, placebo-controlled, double-blind trial

Impact of corticosteroids on the duration of ventilatory support during severe acute exacerbations of chronic obstructive pulmonary disease in patients in the intensive care unit: a study protocol for a multicentre, randomized, placebo-controlled, double-blind trial

Abstract Background Patients who are admitted to the intensive care unit (ICU) for severe acute exacerbations of chronic obstructive pulmonary disease (COPD) have poor outcomes. Although international clinical practice guidelines cautiously recommend the routine use of systemic corticosteroids for C...

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Bibliographic Details
Main Authors: Alexis Ferré, Arnaud W. Thille, Armand Mekontso-Dessap, Thomas Similowski, Stéphane Legriel, Philippe Aegerter, Alexandre Demoule, The Réseau Européen de Recherche en Ventilation Artificielle (REVA) research network
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Trials
Subjects:
Corticosteroids
Exacerbation
COPD
Mechanical ventilation
Mortality
Online Access:https://doi.org/10.1186/s13063-023-07229-9

Internet

https://doi.org/10.1186/s13063-023-07229-9

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