Potential role of the Eph/ephrin system in colorectal cancer: emerging druggable molecular targets

Potential role of the Eph/ephrin system in colorectal cancer: emerging druggable molecular targets

The Eph/ephrin system regulates many developmental processes and adult tissue homeostasis. In colorectal cancer (CRC), it is involved in different processes including tumorigenesis, tumor angiogenesis, metastasis development, and cancer stem cell regeneration. However, conflicting data regarding Eph...

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Bibliographic Details
Main Authors: João Figueira Scarini, Moisés Willian Aparecido Gonçalves, Reydson Alcides de Lima-Souza, Luccas Lavareze, Talita de Carvalho Kimura, Ching-Chu Yang, Albina Altemani, Fernanda Viviane Mariano, Heloisa Prado Soares, Gary Chris Fillmore, Erika Said Abu Egal
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer (CRC)
Eph/ephrin system
pathogenesis
tumor progression
neoangiogenesis
malignant transformation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1275330/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1275330/full

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