The Toll-Like Receptor 4 Antagonist Eritoran Protects Mice from Lethal Filovirus Challenge

ABSTRACT The 2013-2016 outbreak of Ebola virus (EBOV) in West Africa, which has seen intermittent reemergence since it was officially declared over in February of 2016, has demonstrated the need for the rapid development of therapeutic intervention strategies. Indirect evidence has suggested that th...

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Bibliographic Details
Main Authors: Patrick Younan, Palaniappan Ramanathan, Jessica Graber, Fabian Gusovsky, Alexander Bukreyev
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00226-17