CD200-CD200R imbalance correlates with microglia and pro-inflammatory activation in rat spinal cords exposed to amniotic fluid in retinoic acid-induced spina bifida

CD200-CD200R imbalance correlates with microglia and pro-inflammatory activation in rat spinal cords exposed to amniotic fluid in retinoic acid-induced spina bifida

Abstract Spina bifida aperta is a congenital malformation characterized by the failure of neural tube closure resulting in an unprotected fetal spinal cord. The spinal cord then undergoes progressive damage, likely due to chemical and mechanical factors related to exposure to the intrauterine enviro...

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Bibliographic Details
Main Authors: Marc Oria, Rebeca L. Figueira, Federico Scorletti, Lourenco Sbragia, Kathryn Owens, Zhen Li, Bedika Pathak, Maria U. Corona, Mario Marotta, Jose L. Encinas, Jose L. Peiro
Format: Article
Language:English
Published: Nature Portfolio 2018-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-28829-5

Internet

https://doi.org/10.1038/s41598-018-28829-5

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