Tim3 and PD-1 as a therapeutic and prognostic targets in colorectal cancer: Relationship with sidedness, clinicopathological parameters, and survival

Tim3 and PD-1 as a therapeutic and prognostic targets in colorectal cancer: Relationship with sidedness, clinicopathological parameters, and survival

BackgroundColorectal cancer (CRC) is a heterogeneous disease that complicates predicting patients’ prognosis and their response to treatment. CRC prognosis is influenced by the tumor microenvironment (TME). The immune system is a critical component of the TME. Programmed cell death receptor 1 (PD-1)...

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Bibliographic Details
Main Authors: Zahra Mokhtari, Marzieh Rezaei, Mohammad Hossein Sanei, Amirreza Dehghanian, Zahra Faghih, Zahra Heidari, Shirin Tavana
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
immune checkpoints
programmed cell death protein-1
T cell immunoglobulin and mucin-domain containing-3
immunotherapy
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1069696/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1069696/full

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