Phenotypic and functional analysis of γδ T cells in the pathogenesis of human T-cell lymphotropic virus type 1 infection

Phenotypic and functional analysis of γδ T cells in the pathogenesis of human T-cell lymphotropic virus type 1 infection

The human T-cell leukemia virus type 1 (HTLV-1) is the cause of serious malignant and inflammatory diseases, including adult T-cell leukemia and lymphoma and tropical spastic paraparesis. The potential protective role of γδ T cells in HTLV-1 infection remains unclear. Here, demonstrate that there is...

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Bibliographic Details
Main Authors: Matias Ruggieri, Nicolás Ducasa, Claudia Juraske, Virginia Gonzalez Polo, Carolina Berini, Maria Florencia Quiroga, Petros Christopoulos, Susana Minguet, Mirna Biglione, Wolfgang W. Schamel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
γδ T cells
HTLV-1
IFN-γ
mevalonate pathway
cytotoxicity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.920888/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.920888/full

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