Targeting MYC Regulation with Polypurine Reverse Hoogsteen Oligonucleotides

The oncogene MYC has key roles in transcription, proliferation, deregulating cellular energetics, and more. Modulating the expression or function of the MYC protein is a viable therapeutic goal in an array of cancer types, and potential inhibitors of MYC with high specificity and selectivity are of...

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Bibliographic Details
Main Authors: Simonas Valiuska, Alexandra Maria Psaras, Véronique Noé, Tracy A. Brooks, Carlos J. Ciudad
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/1/378