Brodifacoum pharmacokinetics in acute human poisoning: implications for estimating duration of vitamin K therapy

AbstractStandard of care follow-up therapy for patients poisoned by long-acting anticoagulant rodenticides (LAARs) is daily high-dose (up to 100 mg per day) oral vitamin K1 (VK1) for weeks to months to over a year. The availability of CLIA-certified quantitative testing for plasma LAAR concentration...

Full description

Bibliographic Details
Main Authors: Daniel G. Nosal, Richard B. van Breemen, John W. Haffner, Israel Rubinstein, Douglas L. Feinstein
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Toxicology Communications
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/24734306.2021.1887637