Quantification of sterol-specific response in human macrophages using automated imaged-based analysis

Quantification of sterol-specific response in human macrophages using automated imaged-based analysis

Abstract Background The transformation of normal macrophage cells into lipid-laden foam cells is an important step in the progression of atherosclerosis. One major contributor to foam cell formation in vivo is the intracellular accumulation of cholesterol. Methods Here, we report the effects of vari...

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Bibliographic Details
Main Authors: Deborah L. Gater, Namareq Widatalla, Kinza Islam, Maryam AlRaeesi, Jeremy C. M. Teo, Yanthe E. Pearson
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Lipids in Health and Disease
Subjects:
Cholesterol
Ergosterol
Foam cell
Image processing
Lipid droplet
Lysophosphatidylcholine
Online Access:http://link.springer.com/article/10.1186/s12944-017-0629-9

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http://link.springer.com/article/10.1186/s12944-017-0629-9

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