MUC1 Specific Immune Responses Enhanced by Coadministration of Liposomal DDA/MPLA and Lipoglycopeptide

Mucin 1 (MUC1), a well-known tumor-associated antigen and attractive target for tumor immunotherapy, is overexpressed in most human epithelial adenomas with aberrant glycosylation. However, its low immunogenicity impedes the development of MUC1-targeted antitumor vaccines. In this study, we investig...

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Bibliographic Details
Main Authors: Jing-Jing Du, Shi-Hao Zhou, Zi-Ru Cheng, Wen-Bo Xu, Ru-Yan Zhang, Long-Sheng Wang, Jun Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2022.814880/full