Anti-apoptotic effects of minocycline on doxorubicin-induced cardiotoxicity in male Wistar rats

Background and Aim: Doxorubicin is an effective chemotherapeutic agent. However, use of this drug is limited due to its dose-dependent cardiotoxicity. Activation of apoptotic pathways in myocardial tissue plays an important role in doxorubicin- induced cardiotoxicity. Minocycline is an antibiotic th...

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Bibliographic Details
Main Authors: Hossein Piri, Ehsan Aali, Samaneh Keshavarz Hedayati, Sanaz Keshavarz Shahbaz, Yazdan Naderi
Format: Article
Language:fas
Published: Kurdistan University of Medical Sciences 2023-12-01
Series:مجله علمی دانشگاه علوم پزشکی کردستان
Subjects:
Online Access:http://sjku.muk.ac.ir/article-1-7135-en.pdf