Host cells reprogram lipid droplet synthesis through YY1 to resist PRRSV infection

ABSTRACT Metabolism in host cells can be modulated after viral infection, favoring viral survival or clearance. Here, we report that lipid droplet (LD) synthesis in host cells can be modulated by yin yang 1 (YY1) after porcine reproductive and respiratory syndrome virus (PRRSV) infection, resulting...

Full description

Bibliographic Details
Main Authors: Zifang Zheng, Xue Ling, Yang Li, Shuang Qiao, Shuangquan Zhang, Jie Wu, Zhiqian Ma, Mingyu Li, Xuyang Guo, Zhiwei Li, Yingtong Feng, Xiao Liu, Ian G. Goodfellow, Haixue Zheng, Shuqi Xiao
Format: Article
Language:English
Published: American Society for Microbiology 2024-08-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mbio.01549-24