The Yin and Yang of centromeric cohesion of sister chromatids: mitotic kinases meet protein phosphatase 2A

<p>Abstract</p> <p>Accurate chromosome segregation during meiosis and mitosis is essential for the maintenance of genomic stability. Defects in the regulation of chromosome segregation during division predispose cells to undergo mitotic catastrophe or neoplastic transformation. Coh...

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Bibliographic Details
Main Authors: Dai Wei, Wang Xiaoxing
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Cell Division
Online Access:http://www.celldiv.com/content/1/1/9