The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

The transcript cleavage factor paralogue TFS4 is a potent RNA polymerase inhibitor

Transcript cleavage factors such as eukaryotic TFIIS assist the resumption of transcription following RNA pol II backtracking. Here the authors find that one of the Sulfolobus solfataricus TFIIS homolog—TFS4—has evolved into a potent RNA polymerase inhibitor potentially involved in antiviral defense...

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Bibliographic Details
Main Authors: Thomas Fouqueau, Fabian Blombach, Ross Hartman, Alan C. M. Cheung, Mark J. Young, Finn Werner
Format: Article
Language:English
Published: Nature Portfolio 2017-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02081-3

Internet

https://doi.org/10.1038/s41467-017-02081-3

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