In vitro elution characteristics of gentamicin-impregnated Polymethylmethacrylate: premixed with a second powder vs. liquid Lyophilization

In vitro elution characteristics of gentamicin-impregnated Polymethylmethacrylate: premixed with a second powder vs. liquid Lyophilization

Abstract Background Antibiotic-loaded bone cement, or antibiotic-impregnated polymethylmethacrylate (PMMA), were developed to prevent and treat bone and joint infections. Gentamicin is an antibiotic that is commonly used in combination with PMMA; however, gentamicin powder is hard to obtain in many...

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Bibliographic Details
Main Authors: Wongthawat Liawrungrueang, Suwipa Ungphaiboon, Arnurai Jitsurong, Natnicha Ingviya, Boonsin Tangtrakulwanich, Varah Yuenyongviwat
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Musculoskeletal Disorders
Subjects:
Antibiotic spacer
Elution characteristics
Lyophilization
Liquid gentamicin
Online Access:https://doi.org/10.1186/s12891-020-03923-w

Internet

https://doi.org/10.1186/s12891-020-03923-w

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