GSK2606414 Sensitizes ABCG2-Overexpressing Multidrug-Resistant Colorectal Cancer Cells to Chemotherapeutic Drugs

Colorectal cancer is a common malignant tumor. A major factor in the high mortality rate of colorectal cancer is the emergence of multidrug resistance (MDR). Overexpression of the <i>ABCG2</i> gene in cancer cells directly leads to MDR. Finding new inhibitors of ABCG2 may be an effective...

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Bibliographic Details
Main Authors: Ze-Zhong Yu, Bu-Qing Xu, Ying-Ying Wang, Peng-Wei Zhang, Yu-Bin Shu, Zhi Shi
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/11/11/3103