Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model
IntroductionGreen banana flour can be used as a prebiotic due to its ability to promote gut health and provide several health benefits. In this study, we investigated whether feeding mice green banana flour at different doses would alter intestinal microbiota composition.MethodsWe fed C57BL/6N mice...
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2023.1249358/full |
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| author | Ga Hyeon Baek Yu-Jeong Kim Yu-Jeong Kim Yukyung Lee Suk-Chae Jung Hwi Won Seo Jun-Seob Kim |
| author_facet | Ga Hyeon Baek Yu-Jeong Kim Yu-Jeong Kim Yukyung Lee Suk-Chae Jung Hwi Won Seo Jun-Seob Kim |
| author_sort | Ga Hyeon Baek |
| collection | DOAJ |
| description | IntroductionGreen banana flour can be used as a prebiotic due to its ability to promote gut health and provide several health benefits. In this study, we investigated whether feeding mice green banana flour at different doses would alter intestinal microbiota composition.MethodsWe fed C57BL/6N mice either a Low-dose (500 mg/kg/day) or High-dose (2000 mg/kg/day) of green banana flour daily for 3 weeks, and fecal samples were collected on days 0, 14, and 21 for microbiota analysis.ResultsOur results showed that the composition of intestinal microbiota was significantly altered by day 21, regardless of the dose. Notably, the consumption of green banana flour increased the presence of beneficial bacteria, including Coriobacteriaceae_UCG-002, Turicibacter, Parasutterella, Gastranaerophilales_ge, and RF39_ge. These changes in the intestinal microorganisms were accompanied by increased biological processes such as amino acid biosynthesis and secondary metabolite biosynthesis. Conversely, the consumption of green banana flour resulted in a decrease in biological processes related to carbohydrate degradation, glycerol degradation, and similar functions.DiscussionThese results emphasize the potential of green banana flour as a prebiotic that can benefit the gut microbiome. |
| first_indexed | 2024-03-11T14:30:36Z |
| format | Article |
| id | doaj.art-d28b5e43d7d4486bbb2e515edd5e8f85 |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-03-11T14:30:36Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-d28b5e43d7d4486bbb2e515edd5e8f852023-10-31T10:06:08ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2023-10-011010.3389/fnut.2023.12493581249358Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine modelGa Hyeon Baek0Yu-Jeong Kim1Yu-Jeong Kim2Yukyung Lee3Suk-Chae Jung4Hwi Won Seo5Jun-Seob Kim6Department of Nano-Bioengineering, Incheon National University, Incheon, Republic of KoreaInfectious Disease Research Center, KRIBB, Daejeon, Republic of KoreaBiosystems and Bioengineering Program, University of Science and Technology (UST), Daejeon, Republic of KoreaB2S Company Co., Ltd., Seoul, Republic of KoreaDepartment of Bioengineering, University of Illinois Urbana-Champaign, Urbana, IL, United StatesInfectious Disease Research Center, KRIBB, Daejeon, Republic of KoreaDepartment of Nano-Bioengineering, Incheon National University, Incheon, Republic of KoreaIntroductionGreen banana flour can be used as a prebiotic due to its ability to promote gut health and provide several health benefits. In this study, we investigated whether feeding mice green banana flour at different doses would alter intestinal microbiota composition.MethodsWe fed C57BL/6N mice either a Low-dose (500 mg/kg/day) or High-dose (2000 mg/kg/day) of green banana flour daily for 3 weeks, and fecal samples were collected on days 0, 14, and 21 for microbiota analysis.ResultsOur results showed that the composition of intestinal microbiota was significantly altered by day 21, regardless of the dose. Notably, the consumption of green banana flour increased the presence of beneficial bacteria, including Coriobacteriaceae_UCG-002, Turicibacter, Parasutterella, Gastranaerophilales_ge, and RF39_ge. These changes in the intestinal microorganisms were accompanied by increased biological processes such as amino acid biosynthesis and secondary metabolite biosynthesis. Conversely, the consumption of green banana flour resulted in a decrease in biological processes related to carbohydrate degradation, glycerol degradation, and similar functions.DiscussionThese results emphasize the potential of green banana flour as a prebiotic that can benefit the gut microbiome.https://www.frontiersin.org/articles/10.3389/fnut.2023.1249358/fullgreen banana flourprebioticsbeneficial bacteriagut microbiota communitymetabolic pathway prediction |
| spellingShingle | Ga Hyeon Baek Yu-Jeong Kim Yu-Jeong Kim Yukyung Lee Suk-Chae Jung Hwi Won Seo Jun-Seob Kim Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model Frontiers in Nutrition green banana flour prebiotics beneficial bacteria gut microbiota community metabolic pathway prediction |
| title | Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| title_full | Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| title_fullStr | Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| title_full_unstemmed | Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| title_short | Prebiotic potential of green banana flour: impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| title_sort | prebiotic potential of green banana flour impact on gut microbiota modulation and microbial metabolic activity in a murine model |
| topic | green banana flour prebiotics beneficial bacteria gut microbiota community metabolic pathway prediction |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2023.1249358/full |
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