HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism
The RNA binding proteins Rbfox1/2/3 regulate alternative splicing in the nervous system, and disruption of Rbfox1 has been implicated in autism. However, comprehensive identification of functional Rbfox targets has been challenging. Here, we perform HITS-CLIP for all three Rbfox family members in or...
| Main Authors: | , , , , , , , , , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Elsevier
2014-03-01
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| 叢編: | Cell Reports |
| 在線閱讀: | http://www.sciencedirect.com/science/article/pii/S2211124714000849 |