Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study

Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination: Secondary analysis of the randomised CombiVacS study

Summary: Background: The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, and 14-day results showed a strong immune response. The present secondary analysis addresses the evolution of humoral and cellular response up to day...

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Main Authors: Javier García-Pérez, María González-Pérez, María Castillo de la Osa, Alberto M. Borobia, Luis Castaño, María Jesús Bertrán, Magdalena Campins, Antonio Portolés, David Lora, Mercedes Bermejo, Patricia Conde, Lourdes Hernández-Gutierrez, Antonio Carcas, Eunate Arana-Arri, Marta Tortajada, Inmaculada Fuentes, Ana Ascaso, María Teresa García-Morales, Humberto Erick de la Torre-Tarazona, José-Ramón Arribas, Natale Imaz-Ayo, Eugènia Mellado-Pau, Antonia Agustí, Carla Pérez-Ingidua, Agustín Gómez de la Cámara, Jordi Ochando, Cristobal Belda-Iniesta, Jesús Frías, José Alcamí, Mayte Pérez-Olmeda
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:EClinicalMedicine
Subjects:
SARS-CoV-2
Heterologous vaccination
Neutralisation
Variants
Antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537022002590

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http://www.sciencedirect.com/science/article/pii/S2589537022002590

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