Small molecules facilitate single factor-mediated sweat gland cell reprogramming

Small molecules facilitate single factor-mediated sweat gland cell reprogramming

Abstract Background Large skin defects severely disrupt the overall skin structure and can irreversibly damage sweat glands (SG), thus impairing the skin’s physiological function. This study aims to develop a stepwise reprogramming strategy to convert fibroblasts into SG lineages, which may provide...

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Bibliographic Details
Main Authors: Shuai-Fei Ji, Lai-Xian Zhou, Zhi-Feng Sun, Jiang-Bing Xiang, Shao-Yuan Cui, Yan Li, Hua-Ting Chen, Yi-Qiong Liu, Huan-Huan Gao, Xiao-Bing Fu, Xiao-Yan Sun
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Military Medical Research
Subjects:
Direct reprogramming
Human dermal fibroblasts
Sweat gland
Regeneration
Online Access:https://doi.org/10.1186/s40779-022-00372-5

Internet

https://doi.org/10.1186/s40779-022-00372-5

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