Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration

IgG antibodies are some of the most important biopharmaceutical molecules with a high market volume. In spite of the fact that clinical therapies with antibodies are broadly utilized in oncology, immunology and hematology, their delivery strategies and biodistribution need improvement, their limitat...

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Bibliographic Details
Main Authors: Arghavan Soleimanizadeh, Heiko Dinter, Katharina Schindowski
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/10/4/47