The Plant Derived 3-3′-Diindolylmethane (DIM) Behaves as CB<sub>2</sub> Receptor Agonist in Prostate Cancer Cellular Models

3-3′-Diindolylmethane (DIM) is a biologically active dimer derived from the endogenous conversion of indole-3-carbinol (I3C), a naturally occurring glucosinolate found in many cruciferous vegetables (i.e., <i>Brassicaceae</i>). DIM was the first pure androgen receptor antagonist isolated...

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Bibliographic Details
Main Authors: Paolo Tucci, Iain Brown, Guy S. Bewick, Roger G. Pertwee, Pietro Marini
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3620