Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations

Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial-fluid neurocytokine concentrations. Methods: Twe...

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Bibliographic Details
Main Authors: Gastón Andrés Topol, Ines Guerrero Pestalardo, Kenneth Dean Reeves, Fernando Elias, Neven J. Steinmetz, An-Lin Cheng, David Rabago
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Clinics and Practice
Subjects:
glucose
neurogenic inflammation
neuropeptide Y
cytokine
nerve
Online Access:https://www.mdpi.com/2039-7283/12/6/97

Internet

https://www.mdpi.com/2039-7283/12/6/97

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