Dextrose Prolotherapy for Symptomatic Grade IV Knee Osteoarthritis: A Pilot Study of Early and Longer-Term Analgesia and Pain-Specific Cytokine Concentrations
Background: Neurocytokines may upregulate or downregulate neuropathic pain. We hypothesized that dextrose (D-glucose) injections for therapeutic purposes (dextrose prolotherapy: DPT) in painful knee osteoarthritis (KOA) would favorably affect synovial-fluid neurocytokine concentrations. Methods: Twe...
Main Authors: | Gastón Andrés Topol, Ines Guerrero Pestalardo, Kenneth Dean Reeves, Fernando Elias, Neven J. Steinmetz, An-Lin Cheng, David Rabago |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Clinics and Practice |
Subjects: | |
Online Access: | https://www.mdpi.com/2039-7283/12/6/97 |
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