Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

Sex Hormone–Dependent Lipid Mediator Formation in Male and Female Mice During Peritonitis

Introduction: Sex differences in inflammation are obvious and contribute to divergences in the incidence and severity of inflammation-related diseases that frequently preponderate in women. Lipid mediators (LMs), mainly produced by lipoxygenase (LOX) and cyclooxygenase (COX) pathways from polyunsatu...

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Bibliographic Details
Main Authors: Fabiana Troisi, Simona Pace, Paul M. Jordan, Katharina P. L. Meyer, Rossella Bilancia, Armando Ialenti, Francesca Borrelli, Antonietta Rossi, Lidia Sautebin, Charles N. Serhan, Oliver Werz
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
sex differences
lipoxygenase
lipid mediator
specialized pro-resolving mediators
peritonitis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.818544/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.818544/full

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