PQM-1 controls hypoxic survival via regulation of lipid metabolism

Animals respond to hypoxic stress by adjusting metabolic processes to balance survival and reproduction. Here the authors identify the transcription factor PQM-1 as a metabolic regulator that balances hypoxic lipid and carbohydrate metabolism in C. elegans to limit somatic integrity and promote prog...

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Bibliographic Details
Main Authors: Thomas Heimbucher, Julian Hog, Piyush Gupta, Coleen T. Murphy
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18369-w