Single-cell RNA-seq integrated with multi-omics reveals SERPINE2 as a target for metastasis in advanced renal cell carcinoma

Single-cell RNA-seq integrated with multi-omics reveals SERPINE2 as a target for metastasis in advanced renal cell carcinoma

Abstract Tumor growth, metastasis and therapeutic response are believed to be regulated by the tumor and its microenvironment (TME) in advanced renal cell carcinoma (RCC). However, the mechanisms underlying genomic, transcriptomic and epigenetic alternations in RCC progression have not been complete...

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Bibliographic Details
Main Authors: Wen-jin Chen, Ke-qin Dong, Xiu-wu Pan, Si-shun Gan, Da Xu, Jia-xin Chen, Wei-jie Chen, Wen-yan Li, Yu-qi Wang, Wang Zhou, Brian Rini, Xin-gang Cui
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05566-w

Internet

https://doi.org/10.1038/s41419-023-05566-w

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