Ferritinophagy inhibition regulates hypoxia-induced proliferation of pulmonary artery smooth muscle cells

Ferritinophagy inhibition regulates hypoxia-induced proliferation of pulmonary artery smooth muscle cells

Objective To investigate the mechanism of hypoxia-induced free iron reduction in mouse pulmonary artery smooth muscle cells (PASMCs) and its role in the proliferation of PASMCs and pulmonary vascular remodeling. Methods ① Primary mouse PASMCs were cultured and divided into normoxic group(C), normox...

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Bibliographic Details
Main Authors: YIN Chengyang, CHEN Dewei, ZHANG Erlong
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-06-01
Series:陆军军医大学学报
Subjects:
hypoxic pulmonary hypertension
ferritinophagy
pulmonary artery smooth muscle cells
iron homeostasis
cell proliferation
Online Access:http://aammt.tmmu.edu.cn/html/202303076.htm

Internet

http://aammt.tmmu.edu.cn/html/202303076.htm

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