Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium.

Phosphodiesterase-5 inhibition mimics intermittent reoxygenation and improves cardioprotection in the hypoxic myocardium.

<h4>Unlabelled</h4>Although chronic hypoxia is a claimed myocardial risk factor reducing tolerance to ischemia/reperfusion (I/R), intermittent reoxygenation has beneficial effects and enhances heart tolerance to I/R.<h4>Aim of the study</h4>To test the hypothesis that, by mim...

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Bibliographic Details
Main Authors: Giuseppina Milano, Paola Bianciardi, Viviane Rochemont, Giuseppe Vassalli, Ludwig K von Segesser, Antonio F Corno, Marco Guazzi, Michele Samaja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22140481/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22140481/?tool=EBI

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