Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy

Genetic Factors Associated with a Poor Outcome in Head and Neck Cancer Patients Receiving Definitive Chemoradiotherapy

About half of advanced stage head and neck squamous cell carcinoma (HNSCC) patients can be cured by chemoradiotherapy. Patient outcome may be partially determined by the genetic alterations in HNSCC, rendering these alterations promising candidate prognostic factors and/or therapeutic targets. Howev...

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Bibliographic Details
Main Authors: David M. Vossen, Caroline V.M. Verhagen, Martijn van der Heijden, Paul B.M. Essers, Harry Bartelink, Marcel Verheij, Lodewyk F.A. Wessels, Michiel W.M. van den Brekel, Conchita Vens
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
head and neck squamous cell carcinoma
pharyngeal neoplasms
genomics
DNA sequence analysis
mutation
chemoradiotherapy
prognosis
Online Access:https://www.mdpi.com/2072-6694/11/4/445

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https://www.mdpi.com/2072-6694/11/4/445

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