RNA-binding protein CELF6 modulates transcription and splicing levels of genes associated with tumorigenesis in lung cancer A549 cells

RNA-binding protein CELF6 modulates transcription and splicing levels of genes associated with tumorigenesis in lung cancer A549 cells

CELF6 (CUGBP Elav-Like Family Member 6), a canonical RNA binding protein (RBP), plays important roles in post-transcriptional regulation of pre-mRNAs. However, the underlying mechanism of lower expressed CELF6 in lung cancer tissues is still unclear. In this study, we increased CELF6 manually in lun...

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Bibliographic Details
Main Authors: HuSai Ma, GuoWei Liu, Bin Yu, Joshua Wang, YaLi Qi, YiYing Kou, Ying Hu, ShunJun Wang, Fei Wang, Dong Chen
Format: Article
Language:English
Published: PeerJ Inc. 2022-07-01
Series:PeerJ
Subjects:
RNA-Binding Protein
CELF6
Alternative splicing
Lung cancer
RNA-seq
Online Access:https://peerj.com/articles/13800.pdf

Internet

https://peerj.com/articles/13800.pdf

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