Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study.

Recent genome-wide meta-analyses identified 157 loci associated with cross-sectional lipid traits. Here we tested whether these loci associate (singly and in trait-specific genetic risk scores [GRS]) with longitudinal changes in total cholesterol (TC) and triglyceride (TG) levels in a population-bas...

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Bibliographic Details
Main Authors: Tibor V Varga, Emily Sonestedt, Dmitry Shungin, Robert W Koivula, Göran Hallmans, Stefan A Escher, Inês Barroso, Peter Nilsson, Olle Melander, Marju Orho-Melander, Frida Renström, Paul W Franks
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4055682?pdf=render

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http://europepmc.org/articles/PMC4055682?pdf=render

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