The PI3K/Akt/mTOR pathway in lung cancer; oncogenic alterations, therapeutic opportunities, challenges, and a glance at the application of nanoparticles

Lung cancer is the leading cause of cancer-related mortality worldwide. Although the PI3K/Akt/mTOR signaling pathway has recently been considered as one of the most altered molecular pathways in this malignancy, few articles reviewed the task. In this review, we aim to summarize the original data ob...

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Bibliographic Details
Main Authors: Mohammad-Javad Sanaei, Sara Razi, Atieh Pourbagheri-Sigaroodi, Davood Bashash
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523322000262