Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is a complex neurodegenerative disorder and the most common type of dementia. AD is characterized by a decline of cognitive function and brain atrophy, and is highly heritable with estimated heritability ranging from 60 to 80 $$\%$$ % . The most straightf...

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Bibliografiska uppgifter
Huvudupphovsmän: Mansu Kim, Ruiming Wu, Xiaohui Yao, Andrew J. Saykin, Jason H. Moore, Li Shen, for the Alzheimer’s Disease Neuroimaging Initiative
Materialtyp: Artikel
Språk:English
Publicerad: BMC 2022-08-01
Serie:BMC Medical Genomics
Ämnen:
Länkar:https://doi.org/10.1186/s12920-022-01323-8