Understanding the prion-like behavior of mutant p53 proteins in triple-negative breast cancer pathogenesis: The current therapeutic strategies and future directions

Understanding the prion-like behavior of mutant p53 proteins in triple-negative breast cancer pathogenesis: The current therapeutic strategies and future directions

Breast cancer (BC) is viewed as a significant public health issue and is the primary cause of cancer-related deaths among women worldwide. Triple-negative breast cancer (TNBC) is a particularly aggressive subtype that predominantly affects young premenopausal women. The tumor suppressor p53 playsa v...

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Bibliographic Details
Main Authors: Yasaman Naeimzadeh, Amir Tajbakhsh, Jafar Fallahi
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Prion-like aggregation
Triple-negative breast cancer
Mutant p53
Cancer treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024022916

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http://www.sciencedirect.com/science/article/pii/S2405844024022916

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