Development and Validation of UPLC–MS/MS Method for Quantitative Analysis of 5-Fluorouracil in Aqueous Humor of Rabbits

Development and Validation of UPLC–MS/MS Method for Quantitative Analysis of 5-Fluorouracil in Aqueous Humor of Rabbits

5-Fluorouracil (5-FU) is now used in eye drops for the management of conjunctival malignant melanoma, intraepithelial neoplasia, and corneal and conjunctival squamous cell carcinoma. The previously used methods for 5-FU quantification in AqH were time-consuming and less sensitive. Herein, a highly p...

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Bibliographic Details
Main Authors: Mohd Abul Kalam, Sulaiman S. Alhudaithi, Adel Ali Alhowyan, Muzaffar Iqbal, Mohammad Raish, Abdullah K. Alshememry, Musaed Alkholief, Aliyah A. Almomen, Aws Alshamsan
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Separations
Subjects:
5-fluorouracil
allopurinol
aqueous-humor
UPLC–MS/MS
ocular-bioavailability
Online Access:https://www.mdpi.com/2297-8739/10/6/343

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https://www.mdpi.com/2297-8739/10/6/343

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