TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2

The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal disease. CCN2 participates in the regulation of inflammation and fibrosis. TGF-β is considered...

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Bibliographic Details
Main Authors: Raquel Rodrigues-Díez, Sandra Rayego-Mateos, Macarena Orejudo, Luiz Stark Aroeira, Rafael Selgas, Alberto Ortiz, Jesús Egido, Marta Ruiz-Ortega
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/506041