Early-Life Antibiotic Exposure Associated With Varicella Occurrence and Breakthrough Infections: Evidence From Nationwide Pre-Vaccination and Post-Vaccination Cohorts

Early-Life Antibiotic Exposure Associated With Varicella Occurrence and Breakthrough Infections: Evidence From Nationwide Pre-Vaccination and Post-Vaccination Cohorts

BackgroundAntibiotic-driven dysbiosis may impair immune function and reduce vaccine-induced antibody titers.ObjectivesThis study aims to investigate the impacts of early-life antibiotic exposure on subsequent varicella and breakthrough infections.MethodsThis is a nationwide matched cohort study. Fro...

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Bibliographic Details
Main Authors: Teng-Li Lin, Yi-Hsuan Fan, Yi-Ling Chang, Hsiu J. Ho, Li-Lin Liang, Yi-Ju Chen, Chun-Ying Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
varicella
breakthrough infection
vaccine
antibiotic
microbiota
dysbiosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.848835/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.848835/full

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