Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition

Abstract Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency. We sought to investigate whether linear venom epitopes displayed on virus like p...

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Bibliographic Details
Main Authors: Stefanie K. Menzies, Charlotte A. Dawson, Edouard Crittenden, Rebecca J. Edge, Steven R. Hall, Jaffer Alsolaiss, Mark C. Wilkinson, Nicholas R. Casewell, Robert A. Harrison, Stuart Ainsworth
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13376-x

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https://doi.org/10.1038/s41598-022-13376-x

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