<italic toggle="yes">Mycobacterium tuberculosis</italic> Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates
ABSTRACT The protein degradation machinery of Mycobacterium tuberculosis includes a proteasome and a ubiquitin-like protein (Pup). Proteasome accessory factor A (PafA) attaches Pup to proteins to target them for degradation by the proteasome. Free Pup is unstable and never observed in extracts of M....
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2017-03-01
|
Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.00122-17 |