<italic toggle="yes">Mycobacterium tuberculosis</italic> Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates

<italic toggle="yes">Mycobacterium tuberculosis</italic> Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates

ABSTRACT The protein degradation machinery of Mycobacterium tuberculosis includes a proteasome and a ubiquitin-like protein (Pup). Proteasome accessory factor A (PafA) attaches Pup to proteins to target them for degradation by the proteasome. Free Pup is unstable and never observed in extracts of M....

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Bibliographic Details
Main Authors: Susan Zhang, Kristin E. Burns-Huang, Guido V. Janssen, Huilin Li, Huib Ovaa, Lizbeth Hedstrom, K. Heran Darwin
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00122-17

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