Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice

Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice

Abstract Background Innate immunity genes have been reported to affect susceptibility to inflammatory bowel diseases (IBDs) and colitis in mice. Dectin-1, a receptor for fungal cell wall β-glucans, has been clearly implicated in gut microbiota modulation and modification of the susceptibility to gut...

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Bibliographic Details
Main Authors: Yazhou Wang, Madeleine Spatz, Gregory Da Costa, Chloé Michaudel, Alexia Lapiere, Camille Danne, Allison Agus, Marie-Laure Michel, Mihai G. Netea, Philippe Langella, Harry Sokol, Mathias L. Richard
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Microbiome
Subjects:
Microbiota
Gut inflammation
Dectin-1
Dectin-2
Immune response
Online Access:https://doi.org/10.1186/s40168-022-01273-4

Internet

https://doi.org/10.1186/s40168-022-01273-4

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