Direct Ryanodine Receptor-2 Knockout in Primary Afferent Fibers Modestly Affects Neurological Recovery after Contusive Spinal Cord Injury

Direct Ryanodine Receptor-2 Knockout in Primary Afferent Fibers Modestly Affects Neurological Recovery after Contusive Spinal Cord Injury

Neuronal ryanodine receptors (RyR) release calcium from internal stores and play a key role in synaptic plasticity, learning, and memory. Dysregulation of RyR function contributes to neurodegeneration and negatively impacts neurological recovery after spinal cord injury (SCI). However, the individua...

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Bibliographic Details
Main Authors: Ben C. Orem, Johnny R. Morehouse, Spencer Ames, Darlene A. Burke, David S.K. Magnuson, David P. Stirling
Format: Article
Language:English
Published: Mary Ann Liebert 2022-10-01
Series:Neurotrauma Reports
Subjects:
axon degeneration
ryanodine receptor
secondary degeneration
spinal cord injury
Online Access:https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0044

Internet

https://www.liebertpub.com/doi/full/10.1089/NEUR.2022.0044

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